Journal of the American Society of Nephrology
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CURRENT ISSUE ARCHIVES JASN Express ONLINE SUBMISSION


Journal of the American Society of Nephrology - Publish Ahead of Print: [View by date]
Last updated August 23, 2019

Effective with the January 2005 issue of JASN, authors' proofs of accepted articles are published online as they become available via JASN Express. The proofs are presented as fully searchable PDFs, several weeks before their publication in the printed journal or in their final online format. This "publication ahead of print" format allows the publication of articles at a far more rapid pace than in the past.

This publication is an online version of the printed version of JASN. It may not contain all of the information and material contained in the printed version. The information it contains is not necessarily as current as the printed version, and in some instances may be inaccurate or incorrect. The printed version of JASN is the definitive version and, to the extent any differences exist, will prevail over JASN Express.

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Down LETTER TO THE EDITOR
Down EDITORIAL
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To see an article, click its [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


BASIC RESEARCHBack
Dragana Odobasic, Virginie Oudin, Kenji Ito, Poh-Yi Gan, A. Richard Kitching, and Stephen R. Holdsworth
Tolerogenic Dendritic Cells Attenuate Experimental Autoimmune Antimyeloperoxidase Glomerulonephritis
J Am Soc Nephrol published August 23, 2019 as doi:10.1681/ASN.2019030236 [Abstract] [PDF] [Supplemental Data]  

Rory J. Olson, Katharina Hopp, Harrison Wells, Jessica M. Smith, Jessica Furtado, Megan M. Constans, Diana L. Escobar, Aron M. Geurts, Vicente E. Torres, and Peter C. Harris
Synergistic Genetic Interactions between Pkhd1 and Pkd1 Result in an ARPKD-Like Phenotype in Murine Models
J Am Soc Nephrol published August 19, 2019 as doi:10.1681/ASN.2019020150 [Abstract] [PDF] [Supplemental Data]  

Louise K. Farmer, Ruth Rollason, Daniel J. Whitcomb, Lan Ni, Alexander Goodliff, Abigail C. Lay, Lutz Birnbaumer, Kate J. Heesom, Shang-Zhong Xu, Moin A. Saleem, and Gavin I. Welsh
TRPC6 Binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility
J Am Soc Nephrol published August 15, 2019 as doi:10.1681/ASN.2018070729 [Abstract] [PDF] [Supplemental Data]  

Linto Thomas, Jianxiang Xue, Sathish Kumar Murali, Robert A. Fenton, Jessica A. Dominguez Rieg, and Timo Rieg
Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function
J Am Soc Nephrol published August 13, 2019 as doi:10.1681/ASN.2018121250 [Abstract] [PDF] [Supplemental Data]  

Tracy Nelson, Heino Velazquez, Nancy Troiano, and Jackie A. Fretz
Early B Cell Factor 1 (EBF1) Regulates Glomerular Development by Controlling Mesangial Maturation and Consequently COX-2 Expression
J Am Soc Nephrol published August 12, 2019 as doi:10.1681/ASN.2018070699 [Abstract] [PDF] [Supplemental Data]  

Irina V. Grigorieva, Andre Oszwald, Elena F. Grigorieva, Helga Schachner, Barbara Neudert, Tammo Ostendorf, Juergen Floege, Maja T. Lindenmeyer, Clemens D. Cohen, Ulf Panzer, Christof Aigner, Alice Schmidt, Frank Grosveld, Rajesh V. Thakker, Andrew Jackson Rees, and Renate Kain
A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury
J Am Soc Nephrol published August 12, 2019 as doi:10.1681/ASN.2018111143 [Abstract] [PDF] [Supplemental Data]  

Whitney Besse, Alex R. Chang, Jonathan Z. Luo, William J. Triffo, Bryn S. Moore, Ashima Gulati, Dustin N. Hartzel, Shrikant Mane, Regeneron Genetics Center, Vicente E. Torres, Stefan Somlo, Tooraj Mirshahi, Goncalo Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Aris Economides, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Karina Toledo, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Ricardo H. Ulloa, Xiaodong Bai, Suganthi Balasubramanian, Leland Barnard, Andrew Blumenfeld, Yating Chai, Gisu Eom, Lukas Habegger, Young Hahn, Alicia Hawes, Shareef Khalid, Evan K. Maxwell, John Penn, Jeffrey C. Staples, Ashish Yadav, Paloma M. Guzzardo, Marcus B. Jones, and Lyndon J. Mitnaul
ALG9 Mutation Carriers Develop Kidney and Liver Cysts
J Am Soc Nephrol published August 8, 2019 as doi:10.1681/ASN.2019030298 [Abstract] [PDF] [Supplemental Data]  

Manuel Chiusa, Wen Hu, Hong-Jun Liao, Yan Su, Corina M. Borza, Mark P. de Caestecker, Nataliya I. Skrypnyk, Agnes B. Fogo, Vadim Pedchenko, Xiyue Li, Ming-Zhi Zhang, Billy G. Hudson, Trayambak Basak, Roberto M. Vanacore, Roy Zent, and Ambra Pozzi
The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus
J Am Soc Nephrol published August 5, 2019 as doi:10.1681/ASN.2018111160 [Abstract] [PDF] [Supplemental Data]  

Yi Wen, Xiaohan Lu, Jiafa Ren, Jamie R. Privratsky, Bo Yang, Nathan P. Rudemiller, Jiandong Zhang, Robert Griffiths, Mukesh K. Jain, Sergei A. Nedospasov, Bi Cheng Liu, and Steven D. Crowley
KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis
J Am Soc Nephrol published July 23, 2019 as doi:10.1681/ASN.2019020111 [Abstract] [PDF] [Supplemental Data]  

Kurt A. Zimmerman, Cheng J. Song, Zhang Li, Jeremie M. Lever, David K. Crossman, Addison Rains, Ernald J. Aloria, Nancy M. Gonzalez, John R. Bassler, Juling Zhou, Michael R. Crowley, Dustin Z. Revell, Zhaoqi Yan, Dan Shan, Etty N. Benveniste, James F. George, Michal Mrug, and Bradley K. Yoder
Tissue-Resident Macrophages Promote Renal Cystic Disease
J Am Soc Nephrol published July 23, 2019 as doi:10.1681/ASN.2018080810 [Abstract] [PDF] [Supplemental Data]  

Shrikant Ramesh Mulay, Mohsen M. Honarpisheh, Orestes Foresto-Neto, Chongxu Shi, Jyaysi Desai, Zhi Bo Zhao, Julian A. Marschner, Bastian Popper, Ewa Miriam Buhl, Peter Boor, Andreas Linkermann, Helen Liapis, Rostyslav Bilyy, Martin Herrmann, Paola Romagnani, Ilya Belevich, Eija Jokitalo, Jan U. Becker, and Hans-Joachim Anders
Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI
J Am Soc Nephrol published July 19, 2019 as doi:10.1681/ASN.2018121218 [Abstract] [PDF] [Supplemental Data]  

Leyuan Xu, Diana Sharkey, and Lloyd G. Cantley
Tubular GM-CSF Promotes Late MCP-1/CCR2-Mediated Fibrosis and Inflammation after Ischemia/Reperfusion Injury
J Am Soc Nephrol published July 17, 2019 as doi:10.1681/ASN.2019010068 [Abstract] [PDF] [Supplemental Data]  

Jiafa Ren, Jiandong Zhang, Nathan P. Rudemiller, Robert Griffiths, Yi Wen, Xiaohan Lu, Jamie R. Privratsky, Michael D. Gunn, and Steven D. Crowley
Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13–Mediated Matrix Degradation
J Am Soc Nephrol published July 17, 2019 as doi:10.1681/ASN.2018121253 [Abstract] [PDF] [Supplemental Data]  

Bernard M. van den Berg, Gangqi Wang, Margien G. S. Boels, M. Cristina Avramut, Erik Jansen, Wendy M. P. J. Sol, Franck Lebrin, Anton Jan van Zonneveld, Eelco J. P. de Koning, Hans Vink, Hermann-Josef Gröne, Peter Carmeliet, Johan van der Vlag, and Ton J. Rabelink
Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium
J Am Soc Nephrol published July 15, 2019 as doi:10.1681/ASN.2019020192 [Abstract] [PDF] [Supplemental Data]  

Minxian Wang, Justin Chun, Giulio Genovese, Andrea U. Knob, Ava Benjamin, Maris S. Wilkins, David J. Friedman, Gerald B. Appel, Richard P. Lifton, Shrikant Mane, and Martin R. Pollak
Contributions of Rare Gene Variants to Familial and Sporadic FSGS
J Am Soc Nephrol published July 15, 2019 as doi:10.1681/ASN.2019020152 [Abstract] [PDF] [Supplemental Data]  

Taishi Fang, Tai Yeon Koo, Jae-Ghi Lee, Joon Young Jang, Yixuan Xu, Ju Hee Hwang, Sunjoo Park, Ji-Jing Yan, Jung-Hwa Ryu, Yeon-Mi Ryu, Sang-Yeob Kim, Kyung-Suk Suh, and Jaeseok Yang
Anti-CD45RB Antibody Therapy Attenuates Renal Ischemia-Reperfusion Injury by Inducing Regulatory B Cells
J Am Soc Nephrol published July 11, 2019 as doi:10.1681/ASN.2018101067 [Abstract] [PDF] [Supplemental Data]  

Ming-Zhi Zhang, Kensuke Sasaki, Yan Li, Zhilian Li, Yu Pan, Guan-nan Jin, Yinqiu Wang, Aolei Niu, Suwan Wang, Xiaofeng Fan, Jian Chun Chen, Corina Borza, Haichun Yang, Ambra Pozzi, Agnes B. Fogo, and Raymond C. Harris
The Role of the EGF Receptor in Sex Differences in Kidney Injury
J Am Soc Nephrol published July 10, 2019 as doi:10.1681/ASN.2018121244 [Abstract] [PDF] [Supplemental Data]  

Sonia Zambrano, Katja Möller-Hackbarth, Xidan Li, Patricia Q. Rodriguez, Emmanuelle Charrin, Angelina Schwarz, Jenny Nyström, Annika Östman Wernerson, Mark Lal, and Jaakko Patrakka
GPRC5b Modulates Inflammatory Response in Glomerular Diseases via NF-{kappa}B Pathway
J Am Soc Nephrol published July 8, 2019 as doi:10.1681/ASN.2019010089 [Abstract] [PDF] [Supplemental Data]  

Onur K. Polat, Masatoshi Uno, Terukazu Maruyama, Ha Nam Tran, Kayo Imamura, Chee Fah Wong, Reiko Sakaguchi, Mariko Ariyoshi, Kyohei Itsuki, Jun Ichikawa, Takashi Morii, Masahiro Shirakawa, Ryuji Inoue, Katsuhiko Asanuma, Jochen Reiser, Hidehito Tochio, Yasuo Mori, and Masayuki X. Mori
Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes
J Am Soc Nephrol published July 2, 2019 as doi:10.1681/ASN.2018070756 [Abstract] [PDF] [Supplemental Data]  


CLINICAL RESEARCHBack
Dana V. Rizk, Manish K. Saha, Stacy Hall, Lea Novak, Rhubell Brown, Zhi-Qiang Huang, Huma Fatima, Bruce A. Julian, and Jan Novak
Glomerular Immunodeposits of Patients with IgA Nephropathy Are Enriched for IgG Autoantibodies Specific for Galactose-Deficient IgA1
J Am Soc Nephrol published August 23, 2019 as doi:10.1681/ASN.2018111156 [Abstract] [PDF] [Supplemental Data]  

Steven Fishbane, Martin Ford, Masafumi Fukagawa, Kieran McCafferty, Anjay Rastogi, Bruce Spinowitz, Konstantin Staroselskiy, Konstantin Vishnevskiy, Vera Lisovskaja, Ayman Al-Shurbaji, Nicolas Guzman, and Sunil Bhandari
A Phase 3b, Randomized, Double-Blind, Placebo-Controlled Study of Sodium Zirconium Cyclosilicate for Reducing the Incidence of Predialysis Hyperkalemia
J Am Soc Nephrol published June 14, 2019 as doi:10.1681/ASN.2019050450 [Abstract] [PDF] [Supplemental Data]  


LETTER TO THE EDITORBack
Mototsugu Tanaka, Kayo Shinohara, Akiko Ono, and Mutsuhiro Ikuma
ESA Resistance May Be a Potential Confounder for Mortality among Different ESA Types
J Am Soc Nephrol published August 16, 2019 as doi:10.1681/ASN.2019060556 [PDF]  

Guy Rostoker, Fanny Lepeytre, and Jacques Rottembourg
Analysis of Other Confounding Factors Is Mandatory before Considering That Long-Acting Erythropoiesis Stimulating Agents Are Deleterious to Patients on Dialysis
J Am Soc Nephrol published August 16, 2019 as doi:10.1681/ASN.2019050505 [PDF]  

Norio Hanafusa and Ken Tsuchiya
Equivalent Doses Matter, Rather Than Types
J Am Soc Nephrol published August 16, 2019 as doi:10.1681/ASN.2019060569 [PDF]  

Yusuke Sakaguchi, Takayuki Hamano, Atsushi Wada, and Ikuto Masakane
Authors’ Reply
J Am Soc Nephrol published August 16, 2019 as doi:10.1681/ASN.2019050550 [PDF]  


EDITORIALBack
Josephine P. Briggs and Paul M. Palevsky
Clinical Trial Data Sharing: The Time Is Now
J Am Soc Nephrol published August 13, 2019 as doi:10.1681/ASN.2019070731 [PDF]  

Denise K. Marciano
Mesangial Cells: The Tuft Guys of Glomerular Development
J Am Soc Nephrol published August 12, 2019 as doi:10.1681/ASN.2019070724 [PDF]  

Vanessa Grubbs
Another Example of Race Disparities in the US Healthcare System
J Am Soc Nephrol published August 6, 2019 as doi:10.1681/ASN.2019070700 [PDF]  

Rachel E. Patzer and Laura McPherson
Variation in Kidney Transplant Referral: How Much More Evidence Do We Need To Justify Data Collection on Early Transplant Steps?
J Am Soc Nephrol published August 6, 2019 as doi:10.1681/ASN.2019070674 [PDF]  


CLINICAL EPIDEMIOLOGYBack
Yumeng Wen, Changchuan Jiang, Holly M. Koncicki, Carol R. Horowitz, Richard S. Cooper, Aparna Saha, Steven G. Coca, Girish N. Nadkarni, and Lili Chan
Trends and Racial Disparities of Palliative Care Use among Hospitalized Patients with ESKD on Dialysis
J Am Soc Nephrol published August 6, 2019 as doi:10.1681/ASN.2018121256 [Abstract] [PDF] [Supplemental Data]  

S. Joseph Kim, John S. Gill, Greg Knoll, Patricia Campbell, Marcelo Cantarovich, Edward Cole, and Bryce Kiberd
Referral for Kidney Transplantation in Canadian Provinces
J Am Soc Nephrol published August 6, 2019 as doi:10.1681/ASN.2019020127 [Abstract] [PDF] [Supplemental Data]  

Philip A. Clayton, Stephen P. McDonald, Graeme R. Russ, and Steven J. Chadban
Long-Term Outcomes after Acute Rejection in Kidney Transplant Recipients: An ANZDATA Analysis
J Am Soc Nephrol published July 18, 2019 as doi:10.1681/ASN.2018111101 [Abstract] [PDF] [Supplemental Data]  

Tom Greene, Jian Ying, Edward F. Vonesh, Hocine Tighiouart, Andrew S. Levey, Josef Coresh, Jennifer S. Herrick, Enyu Imai, Tazeen H. Jafar, Bart D. Maes, Ronald D. Perrone, Lucia del Vecchio, Jack F.M. Wetzels, Hiddo J.L. Heerspink, and Lesley A. Inker
Performance of GFR Slope as a Surrogate Endpoint for Kidney Disease Progression in Clinical Trials: A Statistical Simulation
J Am Soc Nephrol published July 10, 2019 as doi:10.1681/ASN.2019010009 [Abstract] [PDF] [Supplemental Data]  


META-ANALYSISBack
Morgan E. Grams, Aditya Surapaneni, Shoshana H. Ballew, Lawrence J. Appel, Eric Boerwinkle, L. Ebony Boulware, Teresa K. Chen, Josef Coresh, Mary Cushman, Jasmin Divers, Orlando M. Gutiérrez, Marguerite R. Irvin, Joachim H. Ix, Jeffrey B. Kopp, Lewis H. Kuller, Carl D. Langefeld, Michael S. Lipkowitz, Kenneth J. Mukamal, Solomon K. Musani, Rakhi P. Naik, Nicholas M. Pajewski, Carmen A. Peralta, Adrienne Tin, Christina L. Wassel, James G. Wilson, Cheryl A. Winkler, Bessie A. Young, Neil A. Zakai, and Barry I. Freedman
APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis
J Am Soc Nephrol published August 5, 2019 as doi:10.1681/ASN.2019030240 [Abstract] [PDF] [Supplemental Data]  

Morgan E. Grams, Yingying Sang, Shoshana H. Ballew, Kunihiro Matsushita, Brad C. Astor, Juan Jesus Carrero, Alex R. Chang, Lesley A. Inker, Timothy Kenealy, Csaba P. Kovesdy, Brian J. Lee, Adeera Levin, David Naimark, Michelle J. Pena, Jesse D. Schold, Varda Shalev, Jack F. M. Wetzels, Mark Woodward, Ron T. Gansevoort, Andrew S. Levey, and Josef Coresh
Evaluating Glomerular Filtration Rate Slope as a Surrogate End Point for ESKD in Clinical Trials: An Individual Participant Meta-Analysis of Observational Data
J Am Soc Nephrol published July 10, 2019 as doi:10.1681/ASN.2019010008 [Abstract] [PDF] [Supplemental Data]  

Lesley A. Inker, Hiddo J. L. Heerspink, Hocine Tighiouart, Andrew S. Levey, Josef Coresh, Ron T. Gansevoort, Andrew L. Simon, Jian Ying, Gerald J. Beck, Christoph Wanner, Jürgen Floege, Philip Kam-Tao Li, Vlado Perkovic, Edward F. Vonesh, and Tom Greene
GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Meta-Analysis of Treatment Effects of Randomized Controlled Trials
J Am Soc Nephrol published July 10, 2019 as doi:10.1681/ASN.2019010007 [Abstract] [PDF] [Supplemental Data]  


To see an article, click its [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.



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